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LRRK2 and RIPK2 Variants in the NOD 2-Mediated Signaling Pathway Are Associated with Susceptibility to Mycobacterium leprae in Indian Populations
In recent years, genome wide association studies have discovered a large number of gene loci that play a functional role in innate and adaptive immune pathways associated with leprosy susceptibility. The immunological control of intracellular bacteria M. leprae is modulated by NOD2-mediated signalin...
Autores principales: | Marcinek, Patrick, Jha, Aditya Nath, Shinde, Vidyagouri, Sundaramoorthy, Arun, Rajkumar, Raja, Suryadevara, Naveen Chandra, Neela, Sanjeev Kumar, van Tong, Hoang, Balachander, Vellingiri, Valluri, Vijaya Lakshmi, Thangaraj, Kumarasamy, Velavan, Thirumalaisamy P |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3756038/ https://www.ncbi.nlm.nih.gov/pubmed/24015287 http://dx.doi.org/10.1371/journal.pone.0073103 |
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