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Differentiation from human pluripotent stem cells of cortical neurons of the superficial layers amenable to psychiatric disease modeling and high-throughput drug screening
Cortical neurons of the superficial layers (II-IV) represent a pivotal neuronal population involved in the higher cognitive functions of the human and are particularly affected by psychiatric diseases with developmental manifestations such as schizophrenia and autism. Differentiation protocols of hu...
Autores principales: | Boissart, C, Poulet, A, Georges, P, Darville, H, Julita, E, Delorme, R, Bourgeron, T, Peschanski, M, Benchoua, A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3756296/ https://www.ncbi.nlm.nih.gov/pubmed/23962924 http://dx.doi.org/10.1038/tp.2013.71 |
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