Polycitorols A and B, New Tricyclic Alkaloids from an Ascidian

Two new tricyclic alkaloids, polycitorols A (1) and B (2) have been isolated along with the known lepadiformine (3) from a marine ascidian of the family Polycitoridae. The structures of the new compounds were elucidated by analysis of NMR data and comparison with those of 3 and other related compoun...

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Autores principales: Issa, Hamad H., Tanaka, Junichi, Rachmat, Rachmaniar, Setiawan, Andi, Trianto, Agus, Higa, Tatsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2005
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Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3756322/
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author Issa, Hamad H.
Tanaka, Junichi
Rachmat, Rachmaniar
Setiawan, Andi
Trianto, Agus
Higa, Tatsuo
author_facet Issa, Hamad H.
Tanaka, Junichi
Rachmat, Rachmaniar
Setiawan, Andi
Trianto, Agus
Higa, Tatsuo
author_sort Issa, Hamad H.
collection PubMed
description Two new tricyclic alkaloids, polycitorols A (1) and B (2) have been isolated along with the known lepadiformine (3) from a marine ascidian of the family Polycitoridae. The structures of the new compounds were elucidated by analysis of NMR data and comparison with those of 3 and other related compounds [1–5]. Compounds 1 and 2 are closely related to cylindricines A and B, lacking C-4 oxygenation found in cylindricines and having a butyl instead of a hexyl appendage. NOE experiments on compounds 1 and 2 suggested the A/B ring fusion to be cis.
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spelling pubmed-37563222013-08-29 Polycitorols A and B, New Tricyclic Alkaloids from an Ascidian Issa, Hamad H. Tanaka, Junichi Rachmat, Rachmaniar Setiawan, Andi Trianto, Agus Higa, Tatsuo Mar Drugs Articles Two new tricyclic alkaloids, polycitorols A (1) and B (2) have been isolated along with the known lepadiformine (3) from a marine ascidian of the family Polycitoridae. The structures of the new compounds were elucidated by analysis of NMR data and comparison with those of 3 and other related compounds [1–5]. Compounds 1 and 2 are closely related to cylindricines A and B, lacking C-4 oxygenation found in cylindricines and having a butyl instead of a hexyl appendage. NOE experiments on compounds 1 and 2 suggested the A/B ring fusion to be cis. Molecular Diversity Preservation International (MDPI) 2005-09-23 /pmc/articles/PMC3756322/ Text en © 2005 by MDPI Reproduction is permitted for noncommercial purposes.
spellingShingle Articles
Issa, Hamad H.
Tanaka, Junichi
Rachmat, Rachmaniar
Setiawan, Andi
Trianto, Agus
Higa, Tatsuo
Polycitorols A and B, New Tricyclic Alkaloids from an Ascidian
title Polycitorols A and B, New Tricyclic Alkaloids from an Ascidian
title_full Polycitorols A and B, New Tricyclic Alkaloids from an Ascidian
title_fullStr Polycitorols A and B, New Tricyclic Alkaloids from an Ascidian
title_full_unstemmed Polycitorols A and B, New Tricyclic Alkaloids from an Ascidian
title_short Polycitorols A and B, New Tricyclic Alkaloids from an Ascidian
title_sort polycitorols a and b, new tricyclic alkaloids from an ascidian
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3756322/
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