New Cytotoxic and Antibacterial Compounds Isolated from the Sea Hare, Aplysia kurodai

The extract of the sea hare, Aplysia kurodai, showed cytotoxicity against HeLa cells and antibacterial activity against Staphylococcus aureus. Bioassay-guided purification afforded four active compounds, which were identified to be laurinterol, laurinterol acetate, debromolaurinterol, and debromolau...

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Autores principales: Tsukamoto, Sachiko, Yamashita, Yuko, Ohta, Tomihisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2005
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3756325/
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author Tsukamoto, Sachiko
Yamashita, Yuko
Ohta, Tomihisa
author_facet Tsukamoto, Sachiko
Yamashita, Yuko
Ohta, Tomihisa
author_sort Tsukamoto, Sachiko
collection PubMed
description The extract of the sea hare, Aplysia kurodai, showed cytotoxicity against HeLa cells and antibacterial activity against Staphylococcus aureus. Bioassay-guided purification afforded four active compounds, which were identified to be laurinterol, laurinterol acetate, debromolaurinterol, and debromolaurinterol acetate by spectroscopic analysis. Although the acetates were derived from laurinterol and debromolaurinterol before, this is the first isolation of the acetates from natural sources.
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spelling pubmed-37563252013-08-29 New Cytotoxic and Antibacterial Compounds Isolated from the Sea Hare, Aplysia kurodai Tsukamoto, Sachiko Yamashita, Yuko Ohta, Tomihisa Mar Drugs Articles The extract of the sea hare, Aplysia kurodai, showed cytotoxicity against HeLa cells and antibacterial activity against Staphylococcus aureus. Bioassay-guided purification afforded four active compounds, which were identified to be laurinterol, laurinterol acetate, debromolaurinterol, and debromolaurinterol acetate by spectroscopic analysis. Although the acetates were derived from laurinterol and debromolaurinterol before, this is the first isolation of the acetates from natural sources. Molecular Diversity Preservation International (MDPI) 2005-04-16 /pmc/articles/PMC3756325/ Text en © 2005 by MDPI Reproduction is permitted for noncommercial purposes.
spellingShingle Articles
Tsukamoto, Sachiko
Yamashita, Yuko
Ohta, Tomihisa
New Cytotoxic and Antibacterial Compounds Isolated from the Sea Hare, Aplysia kurodai
title New Cytotoxic and Antibacterial Compounds Isolated from the Sea Hare, Aplysia kurodai
title_full New Cytotoxic and Antibacterial Compounds Isolated from the Sea Hare, Aplysia kurodai
title_fullStr New Cytotoxic and Antibacterial Compounds Isolated from the Sea Hare, Aplysia kurodai
title_full_unstemmed New Cytotoxic and Antibacterial Compounds Isolated from the Sea Hare, Aplysia kurodai
title_short New Cytotoxic and Antibacterial Compounds Isolated from the Sea Hare, Aplysia kurodai
title_sort new cytotoxic and antibacterial compounds isolated from the sea hare, aplysia kurodai
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3756325/
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AT ohtatomihisa newcytotoxicandantibacterialcompoundsisolatedfromtheseahareaplysiakurodai

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