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microRNA-9 targets the long non-coding RNA MALAT1 for degradation in the nucleus

microRNAs regulate the expression of over 60% of protein coding genes by targeting their mRNAs to AGO2-containing complexes in the cytoplasm and promoting their translational inhibition and/or degradation. There is little evidence so far for microRNA-mediated regulation of other classes of non-codin...

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Detalles Bibliográficos
Autores principales: Leucci, Eleonora, Patella, Francesca, Waage, Johannes, Holmstrøm, Kim, Lindow, Morten, Porse, Bo, Kauppinen, Sakari, Lund, Anders H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3756333/
https://www.ncbi.nlm.nih.gov/pubmed/23985560
http://dx.doi.org/10.1038/srep02535