Detection of up to 65% of Precancerous Lesions of the Human Colon and Rectum by Mutation Analysis of APC, K-Ras, B-Raf and CTNNB1

In the present study a recently conceived 4-gene marker panel covering the Wnt and Ras-Raf-MEK-MAPK signaling pathways was used to analyze 20 colorectal serrated lesions and 41 colorectal adenoma samples and to determine the percentage of each of the above-mentioned potentially precancerous lesions...

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Detalles Bibliográficos
Autores principales: Schneider, Mandy, Scholtka, Bettina, Gottschalk, Uwe, Faiss, Siegbert, Schatz, Daniela, Berghof-Jäger, Kornelia, Steinberg, Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3756351/
https://www.ncbi.nlm.nih.gov/pubmed/24212608
http://dx.doi.org/10.3390/cancers3010091

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3756351/
https://www.ncbi.nlm.nih.gov/pubmed/24212608
http://dx.doi.org/10.3390/cancers3010091

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