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Epigenetic Alteration by DNA Promoter Hypermethylation of Genes Related to Transforming Growth Factor-β (TGF-β) Signaling in Cancer

Epigenetic alterations in cancer, especially DNA methylation and histone modification, exert a significant effect on the deregulated expression of cancer-related genes and lay an epigenetic pathway to carcinogenesis and tumor progression. Global hypomethylation and local hypermethylation of CpG isla...

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Detalles Bibliográficos
Autores principales:	Khin, Sann Sanda, Kitazawa, Riko, Kondo, Takeshi, Idei, Yuka, Fujimoto, Masayo, Haraguchi, Ryuma, Mori, Kiyoshi, Kitazawa, Sohei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Molecular Diversity Preservation International (MDPI) 2011
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3756400/ https://www.ncbi.nlm.nih.gov/pubmed/24212650 http://dx.doi.org/10.3390/cancers3010982

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