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Metformin reduces airway glucose permeability and hyperglycaemia-induced Staphylococcus aureus load independently of effects on blood glucose

BACKGROUND: Diabetes is a risk factor for respiratory infection, and hyperglycaemia is associated with increased glucose in airway surface liquid and risk of Staphylococcus aureus infection. OBJECTIVES: To investigate whether elevation of basolateral/blood glucose concentration promotes airway Staph...

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Detalles Bibliográficos
Autores principales:	Garnett, James P, Baker, Emma H, Naik, Sonam, Lindsay, Jodi A, Knight, Gwenan M, Gill, Simren, Tregoning, John S, Baines, Deborah L
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2013
Materias:	Respiratory Infection
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3756442/ https://www.ncbi.nlm.nih.gov/pubmed/23709760 http://dx.doi.org/10.1136/thoraxjnl-2012-203178

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