Cargando…
Mammalian Nemo-like kinase enhances β-catenin-TCF transcription activity in human osteosarcoma and neuroblastoma cells
Nemo-like kinase (NLK) is an evolutionarily conserved serine/threonine kinase and has been considered to be a suppressor of Wnt signaling in mammalian cells. Our study, however, has raised the possibility that NLK also functions as a Wnt signaling activator. In human osteosarcoma and neuroblastoma c...
Autores principales: | Yasuda, Jun, Ichikawa, Hitoshi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Japan Academy
2007
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3756733/ https://www.ncbi.nlm.nih.gov/pubmed/24019581 |
Ejemplares similares
-
Nemo kinase phosphorylates β-catenin to promote ommatidial rotation and connects core PCP factors to E-cadherin–β-catenin
por: Mirkovic, Ivana, et al.
Publicado: (2011) -
Homodimerization of Nemo-like kinase is essential for activation and nuclear localization
por: Ishitani, Shizuka, et al.
Publicado: (2011) -
Diamond Blackfan anemia is mediated by hyperactive Nemo-like kinase
por: Wilkes, M. C., et al.
Publicado: (2020) -
Nuclear Dvl, c-Jun, β-catenin, and TCF form a complex leading to stabiLization of β-catenin–TCF interaction
por: Gan, Xiao-qing, et al.
Publicado: (2008) -
Nemo-Like Kinase in Development and Diseases: Insights from Mouse Studies
por: Daams, Renée, et al.
Publicado: (2020)