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Multifunctional roles of urokinase plasminogen activator (uPA) in cancer stemness and chemoresistance of pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) is almost always lethal. One of the underlying reasons for this lethality is believed to be the presence of cancer stem cells (CSC), which impart chemoresistance and promote recurrence, but the mechanisms responsible are unclear. Recently the poor prognosis of...

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Detalles Bibliográficos
Autores principales:	Asuthkar, Swapna, Stepanova, Victoria, Lebedeva, Tatiana, Holterman, AiXuan L., Estes, Norman, Cines, Douglas B., Rao, Jasti S., Gondi, Christopher S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2013
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3756915/ https://www.ncbi.nlm.nih.gov/pubmed/23864708 http://dx.doi.org/10.1091/mbc.E12-04-0306

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