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Rho GTPase–independent regulation of mitotic progression by the RhoGEF Net1

Neuroepithelial transforming gene 1 (Net1) is a RhoA-subfamily–specific guanine nucleotide exchange factor that is overexpressed in multiple human cancers and is required for proliferation. Molecular mechanisms underlying its role in cell proliferation are unknown. Here we show that overexpression o...

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Detalles Bibliográficos
Autores principales: Menon, Sarita, Oh, Wonkyung, Carr, Heather S., Frost, Jeffrey A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3756918/
https://www.ncbi.nlm.nih.gov/pubmed/23864709
http://dx.doi.org/10.1091/mbc.E13-01-0061