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Rap-afadin axis in control of Rho signaling and endothelial barrier recovery

Activation of the Rho GTPase pathway determines endothelial cell (EC) hyperpermeability after injurious stimuli. To date, feedback mechanisms of Rho down-regulation critical for barrier restoration remain poorly understood. We tested a hypothesis that Rho down-regulation and barrier recovery of agon...

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Detalles Bibliográficos
Autores principales:	Birukova, Anna A., Tian, Xinyong, Tian, Yufeng, Higginbotham, Katherine, Birukov, Konstantin G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2013
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3756920/ https://www.ncbi.nlm.nih.gov/pubmed/23864716 http://dx.doi.org/10.1091/mbc.E13-02-0098

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