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Reggies/flotillins interact with Rab11a and SNX4 at the tubulovesicular recycling compartment and function in transferrin receptor and E-cadherin trafficking

The lipid raft proteins reggie-1 and -2 (flotillins) are implicated in membrane protein trafficking but exactly how has been elusive. We find that reggie-1 and -2 associate with the Rab11a, SNX4, and EHD1–decorated tubulovesicular recycling compartment in HeLa cells and that reggie-1 directly intera...

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Detalles Bibliográficos
Autores principales: Solis, Gonzalo P., Hülsbusch, Nikola, Radon, Yvonne, Katanaev, Vladimir L., Plattner, Helmut, Stuermer, Claudia A. O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3756921/
https://www.ncbi.nlm.nih.gov/pubmed/23825023
http://dx.doi.org/10.1091/mbc.E12-12-0854