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Hypothalamic Programming of Systemic Aging Involving IKKβ/NF-κB and GnRH
Aging is a result of gradual and overall functional deteriorations across the body; however, it is unknown if an individual tissue works to primarily mediate aging progress and lifespan control. Here we found that the hypothalamus is important for the development of whole-body aging in mice, and the...
Autores principales: | Zhang, Guo, Li, Juxue, Purkayastha, Sudarshana, Tang, Yizhe, Zhang, Hai, Yin, Ye, Li, Bo, Liu, Gang, Cai, Dongsheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3756938/ https://www.ncbi.nlm.nih.gov/pubmed/23636330 http://dx.doi.org/10.1038/nature12143 |
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