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CD44 Expression in Intestinal Epithelium and Colorectal Cancer Is Independent of p53 Status
CD44 marks stem cell-like cells in a number of tumour types, including colorectal cancer (CRC), while aberrant CD44 expression conveys increased tumourigenic, invasive, and metastatic potential. Previous data indicate that CD44 is a direct target of p53-mediated transcriptional repression in breast...
Autores principales: | Zeilstra, Jurrit, Joosten, Sander P. J., Vermeulen, Louis, Koster, Jan, Medema, Jan Paul, Versteeg, Rogier, Spaargaren, Marcel, Pals, Steven T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3756983/ https://www.ncbi.nlm.nih.gov/pubmed/24009708 http://dx.doi.org/10.1371/journal.pone.0072849 |
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