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Dissociable Temporo-Parietal Memory Networks Revealed by Functional Connectivity during Episodic Retrieval

Episodic memory retrieval most often recruits multiple separate processes that are thought to involve different temporal regions. Previous studies suggest dissociable regions in the left lateral parietal cortex that are associated with the retrieval processes. Moreover, studies using resting-state f...

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Autores principales: Hirose, Satoshi, Kimura, Hiroko M., Jimura, Koji, Kunimatsu, Akira, Abe, Osamu, Ohtomo, Kuni, Miyashita, Yasushi, Konishi, Seiki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3756987/
https://www.ncbi.nlm.nih.gov/pubmed/24009657
http://dx.doi.org/10.1371/journal.pone.0071210
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author Hirose, Satoshi
Kimura, Hiroko M.
Jimura, Koji
Kunimatsu, Akira
Abe, Osamu
Ohtomo, Kuni
Miyashita, Yasushi
Konishi, Seiki
author_facet Hirose, Satoshi
Kimura, Hiroko M.
Jimura, Koji
Kunimatsu, Akira
Abe, Osamu
Ohtomo, Kuni
Miyashita, Yasushi
Konishi, Seiki
author_sort Hirose, Satoshi
collection PubMed
description Episodic memory retrieval most often recruits multiple separate processes that are thought to involve different temporal regions. Previous studies suggest dissociable regions in the left lateral parietal cortex that are associated with the retrieval processes. Moreover, studies using resting-state functional connectivity (RSFC) have provided evidence for the temporo-parietal memory networks that may support the retrieval processes. In this functional MRI study, we tested functional significance of the memory networks by examining functional connectivity of brain activity during episodic retrieval in the temporal and parietal regions of the memory networks. Recency judgments, judgments of the temporal order of past events, can be achieved by at least two retrieval processes, relational and item-based. Neuroimaging results revealed several temporal and parietal activations associated with relational/item-based recency judgments. Significant RSFC was observed between one parahippocampal region and one left lateral parietal region associated with relational recency judgments, and between four lateral temporal regions and another left lateral parietal region associated with item-based recency judgments. Functional connectivity during task was found to be significant between the parahippocampal region and the parietal region in the RSFC network associated with relational recency judgments. However, out of the four tempo-parietal RSFC networks associated with item-based recency judgments, only one of them (between the left posterior lateral temporal region and the left lateral parietal region) showed significant functional connectivity during task. These results highlight the contrasting roles of the parahippocampal and the lateral temporal regions in recency judgments, and suggest that only a part of the tempo-parietal RSFC networks are recruited to support particular retrieval processes.
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spelling pubmed-37569872013-09-05 Dissociable Temporo-Parietal Memory Networks Revealed by Functional Connectivity during Episodic Retrieval Hirose, Satoshi Kimura, Hiroko M. Jimura, Koji Kunimatsu, Akira Abe, Osamu Ohtomo, Kuni Miyashita, Yasushi Konishi, Seiki PLoS One Research Article Episodic memory retrieval most often recruits multiple separate processes that are thought to involve different temporal regions. Previous studies suggest dissociable regions in the left lateral parietal cortex that are associated with the retrieval processes. Moreover, studies using resting-state functional connectivity (RSFC) have provided evidence for the temporo-parietal memory networks that may support the retrieval processes. In this functional MRI study, we tested functional significance of the memory networks by examining functional connectivity of brain activity during episodic retrieval in the temporal and parietal regions of the memory networks. Recency judgments, judgments of the temporal order of past events, can be achieved by at least two retrieval processes, relational and item-based. Neuroimaging results revealed several temporal and parietal activations associated with relational/item-based recency judgments. Significant RSFC was observed between one parahippocampal region and one left lateral parietal region associated with relational recency judgments, and between four lateral temporal regions and another left lateral parietal region associated with item-based recency judgments. Functional connectivity during task was found to be significant between the parahippocampal region and the parietal region in the RSFC network associated with relational recency judgments. However, out of the four tempo-parietal RSFC networks associated with item-based recency judgments, only one of them (between the left posterior lateral temporal region and the left lateral parietal region) showed significant functional connectivity during task. These results highlight the contrasting roles of the parahippocampal and the lateral temporal regions in recency judgments, and suggest that only a part of the tempo-parietal RSFC networks are recruited to support particular retrieval processes. Public Library of Science 2013-08-29 /pmc/articles/PMC3756987/ /pubmed/24009657 http://dx.doi.org/10.1371/journal.pone.0071210 Text en © 2013 Hirose et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Hirose, Satoshi
Kimura, Hiroko M.
Jimura, Koji
Kunimatsu, Akira
Abe, Osamu
Ohtomo, Kuni
Miyashita, Yasushi
Konishi, Seiki
Dissociable Temporo-Parietal Memory Networks Revealed by Functional Connectivity during Episodic Retrieval
title Dissociable Temporo-Parietal Memory Networks Revealed by Functional Connectivity during Episodic Retrieval
title_full Dissociable Temporo-Parietal Memory Networks Revealed by Functional Connectivity during Episodic Retrieval
title_fullStr Dissociable Temporo-Parietal Memory Networks Revealed by Functional Connectivity during Episodic Retrieval
title_full_unstemmed Dissociable Temporo-Parietal Memory Networks Revealed by Functional Connectivity during Episodic Retrieval
title_short Dissociable Temporo-Parietal Memory Networks Revealed by Functional Connectivity during Episodic Retrieval
title_sort dissociable temporo-parietal memory networks revealed by functional connectivity during episodic retrieval
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3756987/
https://www.ncbi.nlm.nih.gov/pubmed/24009657
http://dx.doi.org/10.1371/journal.pone.0071210
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