The Expression of the Beta Cell-Derived Autoimmune Ligand for the Killer Receptor Nkp46 Is Attenuated in Type 2 Diabetes

NK cells rapidly kill tumor cells, virus infected cells and even self cells. This is mediated via killer receptors, among which NKp46 (NCR1 in mice) is prominent. We have recently demonstrated that in type 1 diabetes (T1D) NK cells accumulate in the diseased pancreas and that they manifest a hypores...

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Detalles Bibliográficos
Autores principales: Gur, Chamutal, Enk, Jonatan, Weitman, Efraim, Bachar, Etty, Suissa, Yaron, Cohen, Guy, Schyr, Rachel Ben-Haroush, Sabanay, Helena, Horwitz, Elad, Glaser, Benjamin, Dor, Yuval, Pribluda, Ariel, Hanna, Jacob H., Leibowitz, Gill, Mandelboim, Ofer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757008/
https://www.ncbi.nlm.nih.gov/pubmed/24009765
http://dx.doi.org/10.1371/journal.pone.0074033

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