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H. pylori CagL-Y58/E59 Prime Higher Integrin α5β1 in Adverse pH Condition to Enhance Hypochlorhydria Vicious Cycle for Gastric Carcinogenesis

BACKGROUND/AIMS: H. pylori CagL amino acid polymorphisms such as Y58/E59 can increase integrin α5β1 expression and gastric cancer risk. Hypochlorhydria during chronic H. pylori infection promotes gastric carcinogenesis. The study test whether CagL-Y58/E59 isolates may regulate integrin α5β1 to trans...

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Detalles Bibliográficos
Autores principales:	Yeh, Yi-Chun, Cheng, Hsiu-Chi, Yang, Hsiao-Bai, Chang, Wei-Lun, Sheu, Bor-Shyang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757014/ https://www.ncbi.nlm.nih.gov/pubmed/24009701 http://dx.doi.org/10.1371/journal.pone.0072735

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