Intact Type I Interferon Production and IRF7 Function in Sooty Mangabeys

In contrast to pathogenic HIV/SIV infections of humans and rhesus macaques (RMs), natural SIV infection of sooty mangabeys (SMs) is typically non-pathogenic despite high viremia. Several studies suggested that low immune activation and relative resistance of CD4+ central memory T-cells from virus in...

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Detalles Bibliográficos
Autores principales: Bosinger, Steven E., Johnson, Zachary P., Folkner, Kathryn A., Patel, Nirav, Hashempour, Tayebeh, Jochems, Simon P., del Rio Estrada, Perla M., Paiardini, Mirko, Lin, Rongtuan, Vanderford, Thomas H., Hiscott, John, Silvestri, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757038/
https://www.ncbi.nlm.nih.gov/pubmed/24009514
http://dx.doi.org/10.1371/journal.ppat.1003597

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