Molecular Cloning and Characterization of Novel Glutamate-Gated Chloride Channel Subunits from Schistosoma mansoni

Cys-loop ligand-gated ion channels (LGICs) mediate fast ionotropic neurotransmission. They are proven drug targets in nematodes and arthropods, but are poorly characterized in flatworms. In this study, we characterized the anion-selective, non-acetylcholine-gated Cys-loop LGICs from Schistosoma mans...

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Detalles Bibliográficos
Autores principales: Dufour, Vanessa, Beech, Robin N., Wever, Claudia, Dent, Joseph A., Geary, Timothy G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757052/
https://www.ncbi.nlm.nih.gov/pubmed/24009509
http://dx.doi.org/10.1371/journal.ppat.1003586

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