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The sst1 Resistance Locus Regulates Evasion of Type I Interferon Signaling by Chlamydia pneumoniae as a Disease Tolerance Mechanism

The sst1, “supersusceptibility to tuberculosis,” locus has previously been shown to be a genetic determinant of host resistance to infection with the intracellular pathogen, Mycobacterium tuberculosis. Chlamydia pneumoniae is an obligate intracellular bacterium associated with community acquired pne...

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Detalles Bibliográficos
Autores principales: He, Xianbao, Berland, Robert, Mekasha, Samrawit, Christensen, Thomas G., Alroy, Joseph, Kramnik, Igor, Ingalls, Robin R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757055/
https://www.ncbi.nlm.nih.gov/pubmed/24009502
http://dx.doi.org/10.1371/journal.ppat.1003569