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Deletion of microRNA-80 Activates Dietary Restriction to Extend C. elegans Healthspan and Lifespan

Caloric/dietary restriction (CR/DR) can promote longevity and protect against age-associated disease across species. The molecular mechanisms coordinating food intake with health-promoting metabolism are thus of significant medical interest. We report that conserved Caenorhabditis elegans microRNA-8...

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Detalles Bibliográficos
Autores principales: Vora, Mehul, Shah, Mitalie, Ostafi, Silvana, Onken, Brian, Xue, Jian, Ni, Julie Zhouli, Gu, Sam, Driscoll, Monica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757059/
https://www.ncbi.nlm.nih.gov/pubmed/24009527
http://dx.doi.org/10.1371/journal.pgen.1003737