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Adhesins of Leptospira interrogans Mediate the Interaction to Fibrinogen and Inhibit Fibrin Clot Formation In Vitro

We report in this work that Leptospira strains, virulent L. interrogans serovar Copenhageni, attenuated L. interrogans serovar Copenhageni and saprophytic L. biflexa serovar Patoc are capable of binding fibrinogen (Fg). The interaction of leptospires with Fg inhibits thrombin- induced fibrin clot fo...

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Detalles Bibliográficos
Autores principales:	Oliveira, Rosane, Domingos, Renan F., Siqueira, Gabriela H., Fernandes, Luis G., Souza, Natalie M., Vieira, Monica L., de Morais, Zenaide M., Vasconcellos, Silvio A., Nascimento, Ana L. T. O.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757074/ https://www.ncbi.nlm.nih.gov/pubmed/24009788 http://dx.doi.org/10.1371/journal.pntd.0002396

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