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Dentate gyrus network dysfunctions precede the symptomatic phase in a genetic mouse model of seizures

Neuronal circuit disturbances that lead to hyperexcitability in the cortico-hippocampal network are one of the landmarks of temporal lobe epilepsy. The dentate gyrus (DG) network plays an important role in regulating the excitability of the entire hippocampus by filtering and integrating information...

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Detalles Bibliográficos
Autores principales: Toader, Oana, Forte, Nicola, Orlando, Marta, Ferrea, Enrico, Raimondi, Andrea, Baldelli, Pietro, Benfenati, Fabio, Medrihan, Lucian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757301/
https://www.ncbi.nlm.nih.gov/pubmed/24009558
http://dx.doi.org/10.3389/fncel.2013.00138