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Immunology of AAV-Mediated Gene Transfer in the Eye

The eye has been at the forefront of translational gene therapy largely owing to suitable disease targets, anatomic accessibility, and well-studied immunologic privilege. These advantages have fostered research culminating in several clinical trials and adeno-associated virus (AAV) has emerged as th...

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Detalles Bibliográficos
Autores principales: Willett, Keirnan, Bennett, Jean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757345/
https://www.ncbi.nlm.nih.gov/pubmed/24009613
http://dx.doi.org/10.3389/fimmu.2013.00261