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Integrative transcriptome analysis reveals dysregulation of canonical cancer molecular pathways in placenta leading to preeclampsia

We previously suggested links between specific XPD mutations in the fetal genome and the risk of placental maldevelopment and preeclampsia, possibly due to impairment of Transcription Factor (TF)IIH-mediated functions in placenta. To identify the underlying mechanisms, we conducted the current integ...

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Detalles Bibliográficos
Autores principales: Moslehi, Roxana, Mills, James L., Signore, Caroline, Kumar, Anil, Ambroggio, Xavier, Dzutsev, Amiran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757356/
https://www.ncbi.nlm.nih.gov/pubmed/23989136
http://dx.doi.org/10.1038/srep02407