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Integrative transcriptome analysis reveals dysregulation of canonical cancer molecular pathways in placenta leading to preeclampsia
We previously suggested links between specific XPD mutations in the fetal genome and the risk of placental maldevelopment and preeclampsia, possibly due to impairment of Transcription Factor (TF)IIH-mediated functions in placenta. To identify the underlying mechanisms, we conducted the current integ...
Autores principales: | Moslehi, Roxana, Mills, James L., Signore, Caroline, Kumar, Anil, Ambroggio, Xavier, Dzutsev, Amiran |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757356/ https://www.ncbi.nlm.nih.gov/pubmed/23989136 http://dx.doi.org/10.1038/srep02407 |
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