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Clinical trials in India: Where do we stand globally?

AIMS: To evaluate the trend of clinical trials in India over the last 4 years compared to the well-established countries using clinical trial registries since the advent of clinical trial registry of India (CTRI). MATERIALS AND METHODS: The data of clinical trials registered in India, United States...

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Autores principales: Selvarajan, Sandhiya, George, Melvin, Kumar, Suresh S, Dkhar, Steven Aibor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757579/
https://www.ncbi.nlm.nih.gov/pubmed/24010056
http://dx.doi.org/10.4103/2229-3485.115373
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author Selvarajan, Sandhiya
George, Melvin
Kumar, Suresh S
Dkhar, Steven Aibor
author_facet Selvarajan, Sandhiya
George, Melvin
Kumar, Suresh S
Dkhar, Steven Aibor
author_sort Selvarajan, Sandhiya
collection PubMed
description AIMS: To evaluate the trend of clinical trials in India over the last 4 years compared to the well-established countries using clinical trial registries since the advent of clinical trial registry of India (CTRI). MATERIALS AND METHODS: The data of clinical trials registered in India, United States (US), and European Union (EU) were obtained from websites of CTRI, clinicaltrial.gov and EU clinical trial registry, respectively from July 20, 2007 to August 29, 2011 for a period of 4 years. Trials registered in Australia, Canada, China, and Japan were obtained from WHO's international clinical trial registry platform for the same period. We used search words for the common diseases such as diabetes, hypertension, etc., RESULTS: The total number of clinical trials registered during the study period was 67,448 across seven study nations. Clinical trials from India constituted only 2.7% of the total number of trials carried out, compared to US constituting 47% of the total number of trials registered, followed by 18% from EU and 11% from Japan. However, India, China, and Japan have been found to show an increase of 3.7%, 5.1%, and 13.1% increase in the number of trials registered in 2011 compared to 2007. In contrast, US and EU showed a decline of 11.3% and 11.95% respectively in the total number of trials registered in 2011 compared to 2007. CONCLUSIONS: Although India shows gradual increase in trials registered since the advent of CTRI, still it continues to lag behind established countries in clinical research.
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spelling pubmed-37575792013-09-05 Clinical trials in India: Where do we stand globally? Selvarajan, Sandhiya George, Melvin Kumar, Suresh S Dkhar, Steven Aibor Perspect Clin Res Original Article AIMS: To evaluate the trend of clinical trials in India over the last 4 years compared to the well-established countries using clinical trial registries since the advent of clinical trial registry of India (CTRI). MATERIALS AND METHODS: The data of clinical trials registered in India, United States (US), and European Union (EU) were obtained from websites of CTRI, clinicaltrial.gov and EU clinical trial registry, respectively from July 20, 2007 to August 29, 2011 for a period of 4 years. Trials registered in Australia, Canada, China, and Japan were obtained from WHO's international clinical trial registry platform for the same period. We used search words for the common diseases such as diabetes, hypertension, etc., RESULTS: The total number of clinical trials registered during the study period was 67,448 across seven study nations. Clinical trials from India constituted only 2.7% of the total number of trials carried out, compared to US constituting 47% of the total number of trials registered, followed by 18% from EU and 11% from Japan. However, India, China, and Japan have been found to show an increase of 3.7%, 5.1%, and 13.1% increase in the number of trials registered in 2011 compared to 2007. In contrast, US and EU showed a decline of 11.3% and 11.95% respectively in the total number of trials registered in 2011 compared to 2007. CONCLUSIONS: Although India shows gradual increase in trials registered since the advent of CTRI, still it continues to lag behind established countries in clinical research. Medknow Publications & Media Pvt Ltd 2013 /pmc/articles/PMC3757579/ /pubmed/24010056 http://dx.doi.org/10.4103/2229-3485.115373 Text en Copyright: © Perspectives in Clinical Research http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Selvarajan, Sandhiya
George, Melvin
Kumar, Suresh S
Dkhar, Steven Aibor
Clinical trials in India: Where do we stand globally?
title Clinical trials in India: Where do we stand globally?
title_full Clinical trials in India: Where do we stand globally?
title_fullStr Clinical trials in India: Where do we stand globally?
title_full_unstemmed Clinical trials in India: Where do we stand globally?
title_short Clinical trials in India: Where do we stand globally?
title_sort clinical trials in india: where do we stand globally?
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757579/
https://www.ncbi.nlm.nih.gov/pubmed/24010056
http://dx.doi.org/10.4103/2229-3485.115373
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