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Pharmacokinetics of single-dose primaquine in patients with chronic kidney dysfunction

AIM: The pharmacokinetics of primaquine has not been studied in special populations. Being a basic compound, preferential binding to alpha-1 acid glycoprotein and substrate for P-glycoprotein, may predispose the drug for an altered pharmacokinetics in states of renal dysfunction. This study attempts...

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Detalles Bibliográficos
Autores principales:	Kulkarni, Shaunak P., Shah, Sanjana R., Kadam, Prashant P., Sridharan, Kannan, Hase, Nivrutti K., Shetty, Partha P., Thatte, Urmila M., Gogtay, Nithya J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Medknow Publications & Media Pvt Ltd 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757598/ https://www.ncbi.nlm.nih.gov/pubmed/24014905 http://dx.doi.org/10.4103/0253-7613.114997

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