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Eyelid Angiosarcoma: A Case Report and Review of the Literature
A 77-year-old woman presented with a 3-month history of a lesion on her left lower eyelid. External examination showed a tan-colored nodule with an overlying crust-covered ulcer on the left lower eyelid, nasally. The ulcer measured 12 mm × 7 mm. Complete surgical excision with a frozen section margi...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Medknow Publications & Media Pvt Ltd
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757639/ https://www.ncbi.nlm.nih.gov/pubmed/24014993 http://dx.doi.org/10.4103/0974-9233.114806 |
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author | Demirci, Hakan Christanson, Murray D. |
author_facet | Demirci, Hakan Christanson, Murray D. |
author_sort | Demirci, Hakan |
collection | PubMed |
description | A 77-year-old woman presented with a 3-month history of a lesion on her left lower eyelid. External examination showed a tan-colored nodule with an overlying crust-covered ulcer on the left lower eyelid, nasally. The ulcer measured 12 mm × 7 mm. Complete surgical excision with a frozen section margin control was performed. Histopathological examination showed islands and sheets of spindle and epithelioid cells with little intervening stroma. The cells had copious amounts of either rounded or tapered eosinophilic cytoplasm with occasional intracytoplasmic lumina and large vesicular nuclei with prominent nucleoli. There was intense immunoreactivity for CD34, CD31, factor VIII, and Ki-67. The diagnosis was eyelid angiosarcoma. The patient refused any further therapy. At 1-year follow-up, there was no recurrence or development of metastasis. In conclusion, tan-colored eyelid nodules with overlying ulcer are usually a basal cell carcinoma; however, rarely it can be an eyelid angiosarcoma. |
format | Online Article Text |
id | pubmed-3757639 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-37576392013-09-06 Eyelid Angiosarcoma: A Case Report and Review of the Literature Demirci, Hakan Christanson, Murray D. Middle East Afr J Ophthalmol Case Report A 77-year-old woman presented with a 3-month history of a lesion on her left lower eyelid. External examination showed a tan-colored nodule with an overlying crust-covered ulcer on the left lower eyelid, nasally. The ulcer measured 12 mm × 7 mm. Complete surgical excision with a frozen section margin control was performed. Histopathological examination showed islands and sheets of spindle and epithelioid cells with little intervening stroma. The cells had copious amounts of either rounded or tapered eosinophilic cytoplasm with occasional intracytoplasmic lumina and large vesicular nuclei with prominent nucleoli. There was intense immunoreactivity for CD34, CD31, factor VIII, and Ki-67. The diagnosis was eyelid angiosarcoma. The patient refused any further therapy. At 1-year follow-up, there was no recurrence or development of metastasis. In conclusion, tan-colored eyelid nodules with overlying ulcer are usually a basal cell carcinoma; however, rarely it can be an eyelid angiosarcoma. Medknow Publications & Media Pvt Ltd 2013 /pmc/articles/PMC3757639/ /pubmed/24014993 http://dx.doi.org/10.4103/0974-9233.114806 Text en Copyright: © Middle East African Journal of Ophthalmology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Demirci, Hakan Christanson, Murray D. Eyelid Angiosarcoma: A Case Report and Review of the Literature |
title | Eyelid Angiosarcoma: A Case Report and Review of the Literature |
title_full | Eyelid Angiosarcoma: A Case Report and Review of the Literature |
title_fullStr | Eyelid Angiosarcoma: A Case Report and Review of the Literature |
title_full_unstemmed | Eyelid Angiosarcoma: A Case Report and Review of the Literature |
title_short | Eyelid Angiosarcoma: A Case Report and Review of the Literature |
title_sort | eyelid angiosarcoma: a case report and review of the literature |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757639/ https://www.ncbi.nlm.nih.gov/pubmed/24014993 http://dx.doi.org/10.4103/0974-9233.114806 |
work_keys_str_mv | AT demircihakan eyelidangiosarcomaacasereportandreviewoftheliterature AT christansonmurrayd eyelidangiosarcomaacasereportandreviewoftheliterature |