A quantitative study of the cell-type specific modulation of c-Rel by hydrogen peroxide and TNF-α

Hydrogen peroxide (H(2)O(2)) at moderate steady-state concentrations synergizes with TNF-α, leading to increased nuclear levels of NF-κB p65 subunit and to a cell-type specific up-regulation of a limited number of NF-κB-dependent genes. Here, we address how H(2)O(2) achieves this molecular specifici...

Descripción completa

Detalles Bibliográficos
Autores principales: Oliveira-Marques, Virgínia, Silva, Teresa, Cunha, Filipa, Covas, Gonçalo, Marinho, H. Susana, Antunes, Fernando, Cyrne, Luísa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2013
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757704/
https://www.ncbi.nlm.nih.gov/pubmed/24024170
http://dx.doi.org/10.1016/j.redox.2013.05.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757704/
https://www.ncbi.nlm.nih.gov/pubmed/24024170
http://dx.doi.org/10.1016/j.redox.2013.05.004

Ejemplares similares