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Rebuilding Pluripotency from Primordial Germ Cells
Mammalian primordial germ cells (PGCs) are unipotent progenitors of the gametes. Nonetheless, they can give rise directly to pluripotent stem cells in vitro or during teratocarcinogenesis. This conversion is inconsistent, however, and has been difficult to study. Here, we delineate requirements for...
Autores principales: | Leitch, Harry G., Nichols, Jennifer, Humphreys, Peter, Mulas, Carla, Martello, Graziano, Lee, Caroline, Jones, Ken, Surani, M. Azim, Smith, Austin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757743/ https://www.ncbi.nlm.nih.gov/pubmed/24052943 http://dx.doi.org/10.1016/j.stemcr.2013.03.004 |
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