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A rare case of haemolytic disease of newborn with Bombay phenotype mother
We are reporting a rare case of severe hemolytic disease of newborn (HDN) with Bombay phenotype mother. A retrospective study of a case with severe haemolytic disease of newborn with Bombay phenotype mother was done. Blood grouping, antibody screening, and lectin study was done on the blood sample o...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757779/ https://www.ncbi.nlm.nih.gov/pubmed/24014949 http://dx.doi.org/10.4103/0973-6247.115583 |
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author | Shastry, Shamee Lewis, Leslie E. Bhat, Sudha S. |
author_facet | Shastry, Shamee Lewis, Leslie E. Bhat, Sudha S. |
author_sort | Shastry, Shamee |
collection | PubMed |
description | We are reporting a rare case of severe hemolytic disease of newborn (HDN) with Bombay phenotype mother. A retrospective study of a case with severe haemolytic disease of newborn with Bombay phenotype mother was done. Blood grouping, antibody screening, and lectin study was done on the blood sample of the baby and mother to confirm the diagnosis. Hematological and biochemical parameters were obtained from the hospital laboratory information system for the analysis. Blood group of the baby was A positive, direct antiglobulin test was negative. Blood group of the mother was confirmed to be Bombay phenotype, Hematological parameters showed all the signs of ongoing hemolysis and the bilirubin level was in the zone of exchange transfusion. Due to the unavailability of this rare phenotype blood unit, baby was managed conservatively. Anticipating the fetal anemia and HDN with mothers having Bombay phenotype and prior notification to the transfusion services will be of great help in optimizing the neonatal care and outcome. |
format | Online Article Text |
id | pubmed-3757779 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-37577792013-09-06 A rare case of haemolytic disease of newborn with Bombay phenotype mother Shastry, Shamee Lewis, Leslie E. Bhat, Sudha S. Asian J Transfus Sci Case Report We are reporting a rare case of severe hemolytic disease of newborn (HDN) with Bombay phenotype mother. A retrospective study of a case with severe haemolytic disease of newborn with Bombay phenotype mother was done. Blood grouping, antibody screening, and lectin study was done on the blood sample of the baby and mother to confirm the diagnosis. Hematological and biochemical parameters were obtained from the hospital laboratory information system for the analysis. Blood group of the baby was A positive, direct antiglobulin test was negative. Blood group of the mother was confirmed to be Bombay phenotype, Hematological parameters showed all the signs of ongoing hemolysis and the bilirubin level was in the zone of exchange transfusion. Due to the unavailability of this rare phenotype blood unit, baby was managed conservatively. Anticipating the fetal anemia and HDN with mothers having Bombay phenotype and prior notification to the transfusion services will be of great help in optimizing the neonatal care and outcome. Medknow Publications & Media Pvt Ltd 2013 /pmc/articles/PMC3757779/ /pubmed/24014949 http://dx.doi.org/10.4103/0973-6247.115583 Text en Copyright: © Asian Journal of Transfusion Science http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Shastry, Shamee Lewis, Leslie E. Bhat, Sudha S. A rare case of haemolytic disease of newborn with Bombay phenotype mother |
title | A rare case of haemolytic disease of newborn with Bombay phenotype mother |
title_full | A rare case of haemolytic disease of newborn with Bombay phenotype mother |
title_fullStr | A rare case of haemolytic disease of newborn with Bombay phenotype mother |
title_full_unstemmed | A rare case of haemolytic disease of newborn with Bombay phenotype mother |
title_short | A rare case of haemolytic disease of newborn with Bombay phenotype mother |
title_sort | rare case of haemolytic disease of newborn with bombay phenotype mother |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757779/ https://www.ncbi.nlm.nih.gov/pubmed/24014949 http://dx.doi.org/10.4103/0973-6247.115583 |
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