Tapentadol hydrochloride: A novel analgesic

Tapentadol is a novel, centrally acting analgesic with dual mechanism of action, combining mu-opioid receptor agonism with noradrenaline reuptake inhibition in the same molecule. It has an improved side effect profile when compared to opioids and nonsteroidal anti-inflammatory drugs. The dual mechan...

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Detalles Bibliográficos
Autores principales: Singh, Dewan Roshan, Nag, Kusha, Shetti, Akshaya N., Krishnaveni, N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757808/
https://www.ncbi.nlm.nih.gov/pubmed/24015138
http://dx.doi.org/10.4103/1658-354X.115319
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author Singh, Dewan Roshan
Nag, Kusha
Shetti, Akshaya N.
Krishnaveni, N.
author_facet Singh, Dewan Roshan
Nag, Kusha
Shetti, Akshaya N.
Krishnaveni, N.
author_sort Singh, Dewan Roshan
collection PubMed
description Tapentadol is a novel, centrally acting analgesic with dual mechanism of action, combining mu-opioid receptor agonism with noradrenaline reuptake inhibition in the same molecule. It has an improved side effect profile when compared to opioids and nonsteroidal anti-inflammatory drugs. The dual mechanism of action makes Tapentadol a useful analgesic to treat acute, chronic, and neuropathic pain.
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spelling pubmed-37578082013-09-06 Tapentadol hydrochloride: A novel analgesic Singh, Dewan Roshan Nag, Kusha Shetti, Akshaya N. Krishnaveni, N. Saudi J Anaesth Review Article Tapentadol is a novel, centrally acting analgesic with dual mechanism of action, combining mu-opioid receptor agonism with noradrenaline reuptake inhibition in the same molecule. It has an improved side effect profile when compared to opioids and nonsteroidal anti-inflammatory drugs. The dual mechanism of action makes Tapentadol a useful analgesic to treat acute, chronic, and neuropathic pain. Medknow Publications & Media Pvt Ltd 2013 /pmc/articles/PMC3757808/ /pubmed/24015138 http://dx.doi.org/10.4103/1658-354X.115319 Text en Copyright: © Saudi Journal of Anaesthesia http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Singh, Dewan Roshan
Nag, Kusha
Shetti, Akshaya N.
Krishnaveni, N.
Tapentadol hydrochloride: A novel analgesic
title Tapentadol hydrochloride: A novel analgesic
title_full Tapentadol hydrochloride: A novel analgesic
title_fullStr Tapentadol hydrochloride: A novel analgesic
title_full_unstemmed Tapentadol hydrochloride: A novel analgesic
title_short Tapentadol hydrochloride: A novel analgesic
title_sort tapentadol hydrochloride: a novel analgesic
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757808/
https://www.ncbi.nlm.nih.gov/pubmed/24015138
http://dx.doi.org/10.4103/1658-354X.115319
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AT nagkusha tapentadolhydrochlorideanovelanalgesic
AT shettiakshayan tapentadolhydrochlorideanovelanalgesic
AT krishnavenin tapentadolhydrochlorideanovelanalgesic

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