CYP2J2 Overexpression Protects against Arrhythmia Susceptibility in Cardiac Hypertrophy

Maladaptive cardiac hypertrophy predisposes one to arrhythmia and sudden death. Cytochrome P450 (CYP)-derived epoxyeicosatrienoic acids (EETs) promote anti-inflammatory and antiapoptotic mechanisms, and are involved in the regulation of cardiac Ca(2+)-, K(+)- and Na(+)-channels. To test the hypothes...

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Detalles Bibliográficos
Autores principales: Westphal, Christina, Spallek, Bastian, Konkel, Anne, Marko, Lajos, Qadri, Fatimunnisa, DeGraff, Laura M., Schubert, Carola, Bradbury, J. Alyce, Regitz-Zagrosek, Vera, Falck, John R., Zeldin, Darryl C., Müller, Dominik N., Schunck, Wolf-Hagen, Fischer, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3758319/
https://www.ncbi.nlm.nih.gov/pubmed/24023684
http://dx.doi.org/10.1371/journal.pone.0073490

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