Inhibition of Oxidative Stress-Elicited AKT Activation Facilitates PPARγ Agonist-Mediated Inhibition of Stem Cell Character and Tumor Growth of Liver Cancer Cells

Emerging evidence suggests that tumor-initiating cells (TICs) are the most malignant cell subpopulation in tumors because of their resistance to chemotherapy or radiation treatment. Targeting TICs may be a key innovation for cancer treatment. In this study, we found that PPARγ agonists inhibited the...

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Detalles Bibliográficos
Autores principales: Liu, Lanlan, Yang, Zhaojuan, Xu, Yingqian, Li, Jingyi, Xu, Dongxu, Zhang, Li, Sun, Jiabin, Xia, Suhua, Zou, Feiyan, Liu, Yongzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3758331/
https://www.ncbi.nlm.nih.gov/pubmed/24023668
http://dx.doi.org/10.1371/journal.pone.0073038

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