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Solar Ultraviolet Irradiation Induces Decorin Degradation in Human Skin Likely via Neutrophil Elastase
Exposure of human skin to solar ultraviolet (UV) irradiation induces matrix metalloproteinase-1 (MMP-1) activity, which degrades type I collagen fibrils. Type I collagen is the most abundant protein in skin and constitutes the majority of skin connective tissue (dermis). Degradation of collagen fibr...
Autores principales: | Li, Yong, Xia, Wei, Liu, Ying, Remmer, Henriette A., Voorhees, John, Fisher, Gary J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3758340/ https://www.ncbi.nlm.nih.gov/pubmed/24023624 http://dx.doi.org/10.1371/journal.pone.0072563 |
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