Primary Pulmonary Poorly Differentiated Synovial Sarcoma: Transducer-Like Enhancer of Split 1 Immunohistochemistry as A Valuable Diagnostic Aid

Poorly differentiated primary pulmonary synovial sarcomas are rare and challenging for a surgical pathologist to diagnose. Although the demonstration of the tumor specific translocation, t (x; 18)(p11.2;q11.2) or the resultant fusion gene (SYT-SSX) is the gold standard for diagnosis, this test is no...

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Autores principales: Kaur, Amulyajit, Tazelaar, Henry Dale, Sahai, Kavita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3758708/
https://www.ncbi.nlm.nih.gov/pubmed/24014971
http://dx.doi.org/10.4103/0974-2727.115922
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author Kaur, Amulyajit
Tazelaar, Henry Dale
Sahai, Kavita
author_facet Kaur, Amulyajit
Tazelaar, Henry Dale
Sahai, Kavita
author_sort Kaur, Amulyajit
collection PubMed
description Poorly differentiated primary pulmonary synovial sarcomas are rare and challenging for a surgical pathologist to diagnose. Although the demonstration of the tumor specific translocation, t (x; 18)(p11.2;q11.2) or the resultant fusion gene (SYT-SSX) is the gold standard for diagnosis, this test is not always accessible. We report the use of immunohistochemistry, including transducer-like enhancer of split-1 in the diagnosis of one such tumor in a young individual.
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spelling pubmed-37587082013-09-06 Primary Pulmonary Poorly Differentiated Synovial Sarcoma: Transducer-Like Enhancer of Split 1 Immunohistochemistry as A Valuable Diagnostic Aid Kaur, Amulyajit Tazelaar, Henry Dale Sahai, Kavita J Lab Physicians Case Report Poorly differentiated primary pulmonary synovial sarcomas are rare and challenging for a surgical pathologist to diagnose. Although the demonstration of the tumor specific translocation, t (x; 18)(p11.2;q11.2) or the resultant fusion gene (SYT-SSX) is the gold standard for diagnosis, this test is not always accessible. We report the use of immunohistochemistry, including transducer-like enhancer of split-1 in the diagnosis of one such tumor in a young individual. Medknow Publications & Media Pvt Ltd 2013 /pmc/articles/PMC3758708/ /pubmed/24014971 http://dx.doi.org/10.4103/0974-2727.115922 Text en Copyright: © Journal of Laboratory Physicians http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Kaur, Amulyajit
Tazelaar, Henry Dale
Sahai, Kavita
Primary Pulmonary Poorly Differentiated Synovial Sarcoma: Transducer-Like Enhancer of Split 1 Immunohistochemistry as A Valuable Diagnostic Aid
title Primary Pulmonary Poorly Differentiated Synovial Sarcoma: Transducer-Like Enhancer of Split 1 Immunohistochemistry as A Valuable Diagnostic Aid
title_full Primary Pulmonary Poorly Differentiated Synovial Sarcoma: Transducer-Like Enhancer of Split 1 Immunohistochemistry as A Valuable Diagnostic Aid
title_fullStr Primary Pulmonary Poorly Differentiated Synovial Sarcoma: Transducer-Like Enhancer of Split 1 Immunohistochemistry as A Valuable Diagnostic Aid
title_full_unstemmed Primary Pulmonary Poorly Differentiated Synovial Sarcoma: Transducer-Like Enhancer of Split 1 Immunohistochemistry as A Valuable Diagnostic Aid
title_short Primary Pulmonary Poorly Differentiated Synovial Sarcoma: Transducer-Like Enhancer of Split 1 Immunohistochemistry as A Valuable Diagnostic Aid
title_sort primary pulmonary poorly differentiated synovial sarcoma: transducer-like enhancer of split 1 immunohistochemistry as a valuable diagnostic aid
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3758708/
https://www.ncbi.nlm.nih.gov/pubmed/24014971
http://dx.doi.org/10.4103/0974-2727.115922
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