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Retinoic acid receptor alpha is associated with tamoxifen resistance in breast cancer

About one-third of oestrogen receptor alpha-positive breast cancer patients treated with tamoxifen relapse. Here we identify the nuclear receptor retinoic acid receptor alpha as a marker of tamoxifen resistance. Using quantitative mass spectrometry-based proteomics, we show that retinoic acid recept...

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Detalles Bibliográficos
Autores principales:	Johansson, Henrik J., Sanchez, Betzabe C., Mundt, Filip, Forshed, Jenny, Kovacs, Aniko, Panizza, Elena, Hultin-Rosenberg, Lina, Lundgren, Bo, Martens, Ulf, Máthé, Gyöngyvér, Yakhini, Zohar, Helou, Khalil, Krawiec, Kamilla, Kanter, Lena, Hjerpe, Anders, Stål, Olle, Linderholm, Barbro K., Lehtiö, Janne
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Pub. Group 2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759040/ https://www.ncbi.nlm.nih.gov/pubmed/23868472 http://dx.doi.org/10.1038/ncomms3175

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