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Toll-like Receptor agonists and alpha-galactosylceramide synergistically enhance the production of interferon-gamma in murine splenocytes
Vα14 natural killer T (iNKT) cells activated by alpha-galactosylceramide (GalCer) secrete a large amount of cytokines. Toll-like receptors (TLRs) play a critical role in the innate immune responses via the recognition of pathological antigen. Previously we demonstrated that the iNKT cells activated...
Autores principales: | Ando, Tatsuya, Ito, Hiroyasu, Ohtaki, Hirofumi, Seishima, Mitsuru |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759050/ https://www.ncbi.nlm.nih.gov/pubmed/23994875 http://dx.doi.org/10.1038/srep02559 |
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