SOX2 promotes dedifferentiation and imparts stem cell-like features to pancreatic cancer cells

SOX2 (Sex-determining region Y (SRY)-Box2) has important functions during embryonic development and is involved in cancer stem cell (CSC) maintenance, in which it impairs cell growth and tumorigenicity. However, the function of SOX2 in pancreatic cancer cells is unclear. The objective of this study...

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Detalles Bibliográficos
Autores principales: Herreros-Villanueva, M, Zhang, J-S, Koenig, A, Abel, E V, Smyrk, T C, Bamlet, W R, de Narvajas, A A-M, Gomez, T S, Simeone, D M, Bujanda, L, Billadeau, D D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759123/
https://www.ncbi.nlm.nih.gov/pubmed/23917223
http://dx.doi.org/10.1038/oncsis.2013.23

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