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Evolution of Tumor Metabolism might Reflect Carcinogenesis as a Reverse Evolution process (Dismantling of Multicellularity)

Carcinogenesis occurs through a series of steps from normal into benign and finally malignant phenotype. This cancer evolutionary trajectory has been accompanied by similar metabolic transformation from normal metabolism into Pasteur and/or Crabtree-Effects into Warburg-Effect and finally Cannibalis...

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Detalles Bibliográficos
Autores principales: Alfarouk, Khalid O., Shayoub, Mohammed E.A., Muddathir, Abdel Khalig, Elhassan, Gamal O., Bashir, Adil H.H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759183/
https://www.ncbi.nlm.nih.gov/pubmed/24310356
http://dx.doi.org/10.3390/cancers3033002