mTORC1 couples immune signals and metabolic programming to establish T(reg) cell function

The mechanistic target of rapamycin (mTOR) pathway integrates diverse environmental inputs, including immune signals and metabolic cues, to direct T cell fate decisions(1). Activation of mTOR, comprised of mTORC1 and mTORC2 complexes, delivers an obligatory signal for proper activation and different...

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Detalles Bibliográficos
Autores principales: Zeng, Hu, Yang, Kai, Cloer, Caryn, Neale, Geoffrey, Vogel, Peter, Chi, Hongbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759242/
https://www.ncbi.nlm.nih.gov/pubmed/23812589
http://dx.doi.org/10.1038/nature12297

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759242/
https://www.ncbi.nlm.nih.gov/pubmed/23812589
http://dx.doi.org/10.1038/nature12297

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