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Dmd(mdx)/Large(myd): a new mouse model of neuromuscular diseases useful for studying physiopathological mechanisms and testing therapies

Although muscular dystrophies are among the most common human genetic disorders, there are few treatment options available. Animal models have become increasingly important for testing new therapies prior to entering human clinical trials. The Dmd(mdx) mouse is the most widely used animal model for...

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Detalles Bibliográficos
Autores principales: Martins, Poliana C. M., Ayub-Guerrieri, Danielle, Martins-Bach, Aurea B., Onofre-Oliveira, Paula, Malheiros, Jackeline M., Tannus, Alberto, de Sousa, Paulo L., Carlier, Pierre G., Vainzof, Mariz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759336/
https://www.ncbi.nlm.nih.gov/pubmed/23798567
http://dx.doi.org/10.1242/dmm.011700