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Dmd(mdx)/Large(myd): a new mouse model of neuromuscular diseases useful for studying physiopathological mechanisms and testing therapies
Although muscular dystrophies are among the most common human genetic disorders, there are few treatment options available. Animal models have become increasingly important for testing new therapies prior to entering human clinical trials. The Dmd(mdx) mouse is the most widely used animal model for...
Autores principales: | Martins, Poliana C. M., Ayub-Guerrieri, Danielle, Martins-Bach, Aurea B., Onofre-Oliveira, Paula, Malheiros, Jackeline M., Tannus, Alberto, de Sousa, Paulo L., Carlier, Pierre G., Vainzof, Mariz |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Limited
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759336/ https://www.ncbi.nlm.nih.gov/pubmed/23798567 http://dx.doi.org/10.1242/dmm.011700 |
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