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Endogenous progesterone levels and frontotemporal dementia: modulation of TDP-43 and Tau levels in vitro and treatment of the A315T TARDBP mouse model

Frontotemporal dementia (FTD) is associated with motor neurone disease (FTD-MND), corticobasal syndrome (CBS) and progressive supranuclear palsy syndrome (PSPS). Together, this group of disorders constitutes a major cause of young-onset dementia. One of the three clinical variants of FTD is progress...

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Detalles Bibliográficos
Autores principales: Dang, Theresa N. T., Dobson-Stone, Carol, Glaros, Elias N., Kim, Woojin S., Hallupp, Marianne, Bartley, Lauren, Piguet, Olivier, Hodges, John R., Halliday, Glenda M., Double, Kay L., Schofield, Peter R., Crouch, Peter J., Kwok, John B. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759339/
https://www.ncbi.nlm.nih.gov/pubmed/23798570
http://dx.doi.org/10.1242/dmm.011460