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Unique Association between Global DNA Hypomethylation and Chromosomal Alterations in Human Hepatocellular Carcinoma

Global DNA hypomethylation is a characteristic feature of cancer cells that closely associates with chromosomal instability (CIN). However, the association between these characteristics during hepatocarcinogenesis remains unclear. Herein, we determined the relationship between hypomethylation and CI...

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Detalles Bibliográficos
Autores principales: Nishida, Naoshi, Kudo, Masatoshi, Nishimura, Takafumi, Arizumi, Tadaaki, Takita, Masahiro, Kitai, Satoshi, Yada, Norihisa, Hagiwara, Satoru, Inoue, Tatsuo, Minami, Yasunori, Ueshima, Kazuomi, Sakurai, Toshiharu, Yokomichi, Naosuke, Nagasaka, Takeshi, Goel, Ajay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759381/
https://www.ncbi.nlm.nih.gov/pubmed/24023736
http://dx.doi.org/10.1371/journal.pone.0072312