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Interleukin-21 Accelerates Thymic Recovery from Glucocorticoïd-Induced Atrophy

Both physiological and psychological stress cause thymic atrophy via glucocorticoïd (GC)-dependent apoptosis of double-positive (DP) thymocytes. Given the pervasiveness of stress, GC-induced thymic atrophy is arguably the most common type of acquired immunodeficiency. We recently reported that inter...

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Detalles Bibliográficos
Autores principales: Rafei, Moutih, Dumont-Lagacé, Maude, Rouette, Alexandre, Perreault, Claude
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759406/
https://www.ncbi.nlm.nih.gov/pubmed/24023776
http://dx.doi.org/10.1371/journal.pone.0072801