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Reliability and Validity of the CogState Battery Chinese Language Version in Schizophrenia

BACKGROUND: Cognitive impairment in patients with schizophrenia is a core symptom of this disease. The computerized CogState Battery (CSB) has been used to detect seven of the most common cognitive domains in schizophrenia. The aim of this study was to examine the reliability and validity of the Chi...

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Autores principales: Zhong, Na, Jiang, Haifeng, Wu, Jin, Chen, Hong, Lin, Shuxing, Zhao, Yan, Du, Jiang, Ma, Xiancang, Chen, Ce, Gao, Chengge, Hashimoto, Kenji, Zhao, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759436/
https://www.ncbi.nlm.nih.gov/pubmed/24023931
http://dx.doi.org/10.1371/journal.pone.0074258
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author Zhong, Na
Jiang, Haifeng
Wu, Jin
Chen, Hong
Lin, Shuxing
Zhao, Yan
Du, Jiang
Ma, Xiancang
Chen, Ce
Gao, Chengge
Hashimoto, Kenji
Zhao, Min
author_facet Zhong, Na
Jiang, Haifeng
Wu, Jin
Chen, Hong
Lin, Shuxing
Zhao, Yan
Du, Jiang
Ma, Xiancang
Chen, Ce
Gao, Chengge
Hashimoto, Kenji
Zhao, Min
author_sort Zhong, Na
collection PubMed
description BACKGROUND: Cognitive impairment in patients with schizophrenia is a core symptom of this disease. The computerized CogState Battery (CSB) has been used to detect seven of the most common cognitive domains in schizophrenia. The aim of this study was to examine the reliability and validity of the Chinese version of the CSB (CSB-C), in Chinese patients with schizophrenia. METHODOLOGY/PRINCIPAL FINDINGS: Sixty Chinese patients with schizophrenia and 58 age, sex, and education matched healthy controls were enrolled. All subjects completed the CSB-C and the Repeated Battery for the Assessment of Neuropsychological Status (RBANS). To examine the test-retest reliability of CSB-C, we tested 33 healthy controls twice, at a one month interval. The Cronbach α value of CSB-C in patients was 0.81. The test-retest correlation coefficients of the Two Back Task, Gronton Maze Learning Task, Social Emotional Cognition Task, and Continuous Paired Association Learning Task were between 0.39 and 0.62 (p<0.01) in healthy controls. The composite scores and all subscores for the CSB-C in patients were significantly (p<0.01) lower than those of healthy controls. Furthermore, composite scores for patients on the RBANS were also significantly lower than those of healthy controls. Interestingly, there was a positive correlation (r  =  0.544, p<0.001) between the composite scores on CSB-C and RBANS for patients. Additionally, in the attention and memory cognitive domains, corresponding subsets from the two batteries correlated significantly (p<0.05). Moreover, factor analysis showed a two-factor model, consisting of speed, memory and reasoning. CONCLUSIONS/SIGNIFICANCE: The CSB-C shows good reliability and validity in measuring the broad cognitive domains of schizophrenia in affected Chinese patients. Therefore, the CSB-C can be used as a cognitive battery, to assess the therapeutic effects of potential cognitive-enhancing agents in this cohort.
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spelling pubmed-37594362013-09-10 Reliability and Validity of the CogState Battery Chinese Language Version in Schizophrenia Zhong, Na Jiang, Haifeng Wu, Jin Chen, Hong Lin, Shuxing Zhao, Yan Du, Jiang Ma, Xiancang Chen, Ce Gao, Chengge Hashimoto, Kenji Zhao, Min PLoS One Research Article BACKGROUND: Cognitive impairment in patients with schizophrenia is a core symptom of this disease. The computerized CogState Battery (CSB) has been used to detect seven of the most common cognitive domains in schizophrenia. The aim of this study was to examine the reliability and validity of the Chinese version of the CSB (CSB-C), in Chinese patients with schizophrenia. METHODOLOGY/PRINCIPAL FINDINGS: Sixty Chinese patients with schizophrenia and 58 age, sex, and education matched healthy controls were enrolled. All subjects completed the CSB-C and the Repeated Battery for the Assessment of Neuropsychological Status (RBANS). To examine the test-retest reliability of CSB-C, we tested 33 healthy controls twice, at a one month interval. The Cronbach α value of CSB-C in patients was 0.81. The test-retest correlation coefficients of the Two Back Task, Gronton Maze Learning Task, Social Emotional Cognition Task, and Continuous Paired Association Learning Task were between 0.39 and 0.62 (p<0.01) in healthy controls. The composite scores and all subscores for the CSB-C in patients were significantly (p<0.01) lower than those of healthy controls. Furthermore, composite scores for patients on the RBANS were also significantly lower than those of healthy controls. Interestingly, there was a positive correlation (r  =  0.544, p<0.001) between the composite scores on CSB-C and RBANS for patients. Additionally, in the attention and memory cognitive domains, corresponding subsets from the two batteries correlated significantly (p<0.05). Moreover, factor analysis showed a two-factor model, consisting of speed, memory and reasoning. CONCLUSIONS/SIGNIFICANCE: The CSB-C shows good reliability and validity in measuring the broad cognitive domains of schizophrenia in affected Chinese patients. Therefore, the CSB-C can be used as a cognitive battery, to assess the therapeutic effects of potential cognitive-enhancing agents in this cohort. Public Library of Science 2013-09-02 /pmc/articles/PMC3759436/ /pubmed/24023931 http://dx.doi.org/10.1371/journal.pone.0074258 Text en © 2013 Zhong et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Zhong, Na
Jiang, Haifeng
Wu, Jin
Chen, Hong
Lin, Shuxing
Zhao, Yan
Du, Jiang
Ma, Xiancang
Chen, Ce
Gao, Chengge
Hashimoto, Kenji
Zhao, Min
Reliability and Validity of the CogState Battery Chinese Language Version in Schizophrenia
title Reliability and Validity of the CogState Battery Chinese Language Version in Schizophrenia
title_full Reliability and Validity of the CogState Battery Chinese Language Version in Schizophrenia
title_fullStr Reliability and Validity of the CogState Battery Chinese Language Version in Schizophrenia
title_full_unstemmed Reliability and Validity of the CogState Battery Chinese Language Version in Schizophrenia
title_short Reliability and Validity of the CogState Battery Chinese Language Version in Schizophrenia
title_sort reliability and validity of the cogstate battery chinese language version in schizophrenia
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759436/
https://www.ncbi.nlm.nih.gov/pubmed/24023931
http://dx.doi.org/10.1371/journal.pone.0074258
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