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Reliability and Validity of the CogState Battery Chinese Language Version in Schizophrenia
BACKGROUND: Cognitive impairment in patients with schizophrenia is a core symptom of this disease. The computerized CogState Battery (CSB) has been used to detect seven of the most common cognitive domains in schizophrenia. The aim of this study was to examine the reliability and validity of the Chi...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759436/ https://www.ncbi.nlm.nih.gov/pubmed/24023931 http://dx.doi.org/10.1371/journal.pone.0074258 |
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author | Zhong, Na Jiang, Haifeng Wu, Jin Chen, Hong Lin, Shuxing Zhao, Yan Du, Jiang Ma, Xiancang Chen, Ce Gao, Chengge Hashimoto, Kenji Zhao, Min |
author_facet | Zhong, Na Jiang, Haifeng Wu, Jin Chen, Hong Lin, Shuxing Zhao, Yan Du, Jiang Ma, Xiancang Chen, Ce Gao, Chengge Hashimoto, Kenji Zhao, Min |
author_sort | Zhong, Na |
collection | PubMed |
description | BACKGROUND: Cognitive impairment in patients with schizophrenia is a core symptom of this disease. The computerized CogState Battery (CSB) has been used to detect seven of the most common cognitive domains in schizophrenia. The aim of this study was to examine the reliability and validity of the Chinese version of the CSB (CSB-C), in Chinese patients with schizophrenia. METHODOLOGY/PRINCIPAL FINDINGS: Sixty Chinese patients with schizophrenia and 58 age, sex, and education matched healthy controls were enrolled. All subjects completed the CSB-C and the Repeated Battery for the Assessment of Neuropsychological Status (RBANS). To examine the test-retest reliability of CSB-C, we tested 33 healthy controls twice, at a one month interval. The Cronbach α value of CSB-C in patients was 0.81. The test-retest correlation coefficients of the Two Back Task, Gronton Maze Learning Task, Social Emotional Cognition Task, and Continuous Paired Association Learning Task were between 0.39 and 0.62 (p<0.01) in healthy controls. The composite scores and all subscores for the CSB-C in patients were significantly (p<0.01) lower than those of healthy controls. Furthermore, composite scores for patients on the RBANS were also significantly lower than those of healthy controls. Interestingly, there was a positive correlation (r = 0.544, p<0.001) between the composite scores on CSB-C and RBANS for patients. Additionally, in the attention and memory cognitive domains, corresponding subsets from the two batteries correlated significantly (p<0.05). Moreover, factor analysis showed a two-factor model, consisting of speed, memory and reasoning. CONCLUSIONS/SIGNIFICANCE: The CSB-C shows good reliability and validity in measuring the broad cognitive domains of schizophrenia in affected Chinese patients. Therefore, the CSB-C can be used as a cognitive battery, to assess the therapeutic effects of potential cognitive-enhancing agents in this cohort. |
format | Online Article Text |
id | pubmed-3759436 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-37594362013-09-10 Reliability and Validity of the CogState Battery Chinese Language Version in Schizophrenia Zhong, Na Jiang, Haifeng Wu, Jin Chen, Hong Lin, Shuxing Zhao, Yan Du, Jiang Ma, Xiancang Chen, Ce Gao, Chengge Hashimoto, Kenji Zhao, Min PLoS One Research Article BACKGROUND: Cognitive impairment in patients with schizophrenia is a core symptom of this disease. The computerized CogState Battery (CSB) has been used to detect seven of the most common cognitive domains in schizophrenia. The aim of this study was to examine the reliability and validity of the Chinese version of the CSB (CSB-C), in Chinese patients with schizophrenia. METHODOLOGY/PRINCIPAL FINDINGS: Sixty Chinese patients with schizophrenia and 58 age, sex, and education matched healthy controls were enrolled. All subjects completed the CSB-C and the Repeated Battery for the Assessment of Neuropsychological Status (RBANS). To examine the test-retest reliability of CSB-C, we tested 33 healthy controls twice, at a one month interval. The Cronbach α value of CSB-C in patients was 0.81. The test-retest correlation coefficients of the Two Back Task, Gronton Maze Learning Task, Social Emotional Cognition Task, and Continuous Paired Association Learning Task were between 0.39 and 0.62 (p<0.01) in healthy controls. The composite scores and all subscores for the CSB-C in patients were significantly (p<0.01) lower than those of healthy controls. Furthermore, composite scores for patients on the RBANS were also significantly lower than those of healthy controls. Interestingly, there was a positive correlation (r = 0.544, p<0.001) between the composite scores on CSB-C and RBANS for patients. Additionally, in the attention and memory cognitive domains, corresponding subsets from the two batteries correlated significantly (p<0.05). Moreover, factor analysis showed a two-factor model, consisting of speed, memory and reasoning. CONCLUSIONS/SIGNIFICANCE: The CSB-C shows good reliability and validity in measuring the broad cognitive domains of schizophrenia in affected Chinese patients. Therefore, the CSB-C can be used as a cognitive battery, to assess the therapeutic effects of potential cognitive-enhancing agents in this cohort. Public Library of Science 2013-09-02 /pmc/articles/PMC3759436/ /pubmed/24023931 http://dx.doi.org/10.1371/journal.pone.0074258 Text en © 2013 Zhong et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited. |
spellingShingle | Research Article Zhong, Na Jiang, Haifeng Wu, Jin Chen, Hong Lin, Shuxing Zhao, Yan Du, Jiang Ma, Xiancang Chen, Ce Gao, Chengge Hashimoto, Kenji Zhao, Min Reliability and Validity of the CogState Battery Chinese Language Version in Schizophrenia |
title | Reliability and Validity of the CogState Battery Chinese Language Version in Schizophrenia |
title_full | Reliability and Validity of the CogState Battery Chinese Language Version in Schizophrenia |
title_fullStr | Reliability and Validity of the CogState Battery Chinese Language Version in Schizophrenia |
title_full_unstemmed | Reliability and Validity of the CogState Battery Chinese Language Version in Schizophrenia |
title_short | Reliability and Validity of the CogState Battery Chinese Language Version in Schizophrenia |
title_sort | reliability and validity of the cogstate battery chinese language version in schizophrenia |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759436/ https://www.ncbi.nlm.nih.gov/pubmed/24023931 http://dx.doi.org/10.1371/journal.pone.0074258 |
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