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Micronodular Thymoma with Lymphoid Stroma in a Multilocular Thymic Cyst: A Case Study
Herein, we report a case of micronodular thymoma with lymphoid stroma in a previously healthy 73-year-old male. Thymectomy was performed. The solid and macrocystic masses were encapsulated with focal invasion. The solid portion consisted of nodules of bland-looking spindle or round epithelial cells...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Society of Pathologists and The Korean Society for Cytopathology
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759641/ https://www.ncbi.nlm.nih.gov/pubmed/24009637 http://dx.doi.org/10.4132/KoreanJPathol.2013.47.4.392 |
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author | Kim, Na Rae Lee, Jae Ik Ha, Seung Yeon |
author_facet | Kim, Na Rae Lee, Jae Ik Ha, Seung Yeon |
author_sort | Kim, Na Rae |
collection | PubMed |
description | Herein, we report a case of micronodular thymoma with lymphoid stroma in a previously healthy 73-year-old male. Thymectomy was performed. The solid and macrocystic masses were encapsulated with focal invasion. The solid portion consisted of nodules of bland-looking spindle or round epithelial cells in lymphoid stroma containing prominent germinal centers. The epithelial cells had moderate amount of cytoplasm and occasional mucin production. The cystic portion was lined with cuboidal epithelium. According to World Health Organization (WHO) classification, the mass was diagnosed as a micronodular thymoma with lymphoid stroma accompanied by a pre-existing multilocular thymic cyst. Micronodular thymoma with lymphoid stroma, a possible variant of type A thymoma, is an extremely rare tumor. This so-called "unusual" variant may imply the schematic weakness of the current WHO classification that cannot cover all morphologic types. Further study is recommended for clarification of this variant and its incorporation into the current classification. |
format | Online Article Text |
id | pubmed-3759641 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | The Korean Society of Pathologists and The Korean Society for Cytopathology |
record_format | MEDLINE/PubMed |
spelling | pubmed-37596412013-09-04 Micronodular Thymoma with Lymphoid Stroma in a Multilocular Thymic Cyst: A Case Study Kim, Na Rae Lee, Jae Ik Ha, Seung Yeon Korean J Pathol Case Study Herein, we report a case of micronodular thymoma with lymphoid stroma in a previously healthy 73-year-old male. Thymectomy was performed. The solid and macrocystic masses were encapsulated with focal invasion. The solid portion consisted of nodules of bland-looking spindle or round epithelial cells in lymphoid stroma containing prominent germinal centers. The epithelial cells had moderate amount of cytoplasm and occasional mucin production. The cystic portion was lined with cuboidal epithelium. According to World Health Organization (WHO) classification, the mass was diagnosed as a micronodular thymoma with lymphoid stroma accompanied by a pre-existing multilocular thymic cyst. Micronodular thymoma with lymphoid stroma, a possible variant of type A thymoma, is an extremely rare tumor. This so-called "unusual" variant may imply the schematic weakness of the current WHO classification that cannot cover all morphologic types. Further study is recommended for clarification of this variant and its incorporation into the current classification. The Korean Society of Pathologists and The Korean Society for Cytopathology 2013-08 2013-08-26 /pmc/articles/PMC3759641/ /pubmed/24009637 http://dx.doi.org/10.4132/KoreanJPathol.2013.47.4.392 Text en © 2013 The Korean Society of Pathologists/The Korean Society for Cytopathology http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Study Kim, Na Rae Lee, Jae Ik Ha, Seung Yeon Micronodular Thymoma with Lymphoid Stroma in a Multilocular Thymic Cyst: A Case Study |
title | Micronodular Thymoma with Lymphoid Stroma in a Multilocular Thymic Cyst: A Case Study |
title_full | Micronodular Thymoma with Lymphoid Stroma in a Multilocular Thymic Cyst: A Case Study |
title_fullStr | Micronodular Thymoma with Lymphoid Stroma in a Multilocular Thymic Cyst: A Case Study |
title_full_unstemmed | Micronodular Thymoma with Lymphoid Stroma in a Multilocular Thymic Cyst: A Case Study |
title_short | Micronodular Thymoma with Lymphoid Stroma in a Multilocular Thymic Cyst: A Case Study |
title_sort | micronodular thymoma with lymphoid stroma in a multilocular thymic cyst: a case study |
topic | Case Study |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759641/ https://www.ncbi.nlm.nih.gov/pubmed/24009637 http://dx.doi.org/10.4132/KoreanJPathol.2013.47.4.392 |
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